49ers 2025 Schedule Pdf Download. The schedule will also include matchups with every team from. Their.549 opponent winning percentage is tied for the highest mark in.

The san francisco 49ers’ week 17 loss to the detroit lions officially locked the team into last place in the nfc west, regardless of the outcome of their week 18 matchup against the. The san francisco 49ers will receive a slight reprieve in the 2025 season thanks to their abysmal 2024 campaign.